Fabrication of Biocompatible Surface through Fixation of Silver Nanoparticles Assembled on Polyurethane

Document Type : Research Paper


Iranian-Australian Community of Science, Tehran, Iran


Development of simple and reliable protocols for the immobilization of enzymes is an important aspect of nano biotechnology. Silver nanoparticles are known to bind enzymes, but reuse characteristics of the silver nano-enzyme bioconjugates has hithero been poor. In this paper, we demonstrate that silver nanoparticles bound at high surface coverage on polyurethane.  This material can be washed, dried, and stored for extended periods without the loss of nanoparticles. The performance of the material is as an antibacterial filter   The silver nanoparticle coated on polyurethane then act as templates for the immobilization of the enzyme butyrylcholinesterase (BuChE). BuChE in the bioconjugate system shows enhanced stability toward harsh temperature and pH conditions.


Volume 04, Issue 01
March 2020
Pages 30-35
  • Receive Date: 28 December 2019
  • Revise Date: 20 January 2020
  • Accept Date: 11 February 2020
  • First Publish Date: 01 March 2020